History of Science and Engineering Annotation << Back INORGANIC POLYPHOSPHATES AS UNIVERSAL REGULATORY COMPOUNDS IN LIVING CELLS T.V. Kulakovskaya The article is devoted to research in biochemistry and cell biology of inorganic polyphosphates in IBPM RAS. These biopolymers are reserves of phosphate and energy involved in the regulation of gene expression and stress adaptation in the cells of living organisms, from bacteria to human. Long-term studies led by Corresponding Member of RAS I.S. Kulaev formed the concept of multiple localization and functional signifi cance of these polymers in the microbial cell, including participation in the regulation of the biosynthesis of antibiotics, toxic compounds tolerance and degradation of xenobiotics. Polyphosphates are involved in the cascade of blood coagulation, bone development and signal transduction. Microorganisms are a good model for the study of metabolic pathways of these compounds in a changing environment. Keywords: polyphosphate; microorganism; enzyme; cellular role. Contacts: E-mail: alla@ibpm.pushchino.ru Pp. 86-90.